… its effect through the action on alpha-2 adrenergic receptors. The sedative … than
treatment for medetomidine induced bradycardia. … The antinociceptive action of an alpha-2-adrenoceptor …

… a different spinal segment, and (iii) projecting neurons, which terminate within supraspinal
structures… Central noradrenergic pathways, particularly those mediated by alpha-2 adrenergic …

… It is important to consider the goals and outcomes of any intervention(s) for both acute and
… pain as a ‘syndrome’ with poorly established mechanisms and a variety of clinical signs. …

… Opioids act on three levels: they suppress transmission in the dorsal horn, inhibit somatosensory
afferents in the supraspinal portion and activate the descending inhibitory pathways. …

Amaç: Tavşanlarda daha önce hiç uygulanmamış iki farklı anestezik kombinasyonun yani
ketamin- deksmedetomidin- midazolam- butorfanol ve ketamin- deksmedetomidin-midazolam- …